Bruce Abrahamse

Bruce Abrahamse

April 26, 2025

3 Morning Supplements That May Help to ‘Slow Down’ Aging And ‘Promote Longevity

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The effects of aging are not something we typically think about much when we are younger. Yet, once you hit a certain age, you start to notice the signs of aging, both externally and internally. Therefore, it’s no surprise that we are always looking for ways to effectively slow aging down as much as possible. You just have to walk down any pharmacy aisle to see how many products offer the promise of younger-looking skin or improved energy. Do any of these products really work, though, and which ones should you incorporate into your morning routine?

Can We Slow Aging Down?

an elderly lady
Credit: Pixabay

Aging is, unfortunately, an inevitable part of life. As we get older, our bodies start to slow down, impacting everything from the elasticity of our skin to our energy levels. However, while we cannot escape it, we can slow down the process considerably. No product on the market can completely stop your body from aging. However, there are certain supplements that may assist in supporting your body’s defenses against the signs of aging. These supplements are full of the vitamins, antioxidants, and anti-inflammatory properties required to make your skin healthier, boost the regeneration of cells, and reduce the visible signs of aging. It’s important to take these supplements as part of an overall balanced routine and diet. According to neuroscientists, there are three specific supplements you should be adding to your morning routine. 

Resveratrol

red grapes
Credit: Pixabay

Resveratrol is one of the most extensively researched compounds in the fields of anti-aging and longevity science. It is a type of antioxidant known as a polyphenol, naturally found in the skin of red grapes, red wine, certain berries, and peanuts. This compound is produced by plants in response to stress, injury, or fungal infection. When consumed by humans, resveratrol appears to offer similar protective benefits at the cellular level.

One notable study published in Nature found that mice fed a high-calorie diet lived longer and experienced improved overall health when given resveratrol, particularly when dosed every other day. These mice showed enhanced cardiovascular health, better motor coordination, and improved insulin sensitivity.

Another study demonstrated that resveratrol activates the SIRT1 enzyme, which is associated with longevity. In aging mice, this activation led to improved muscle function, reduced cardiac hypertrophy, and restoration of autophagy in skeletal muscle.

However, the effects of resveratrol can vary depending on diet. For instance, a study on aged mice revealed that while resveratrol improved insulin sensitivity in those on a standard diet, it actually had adverse effects on arterial function in mice consuming a high-protein diet.

For those considering resveratrol supplementation to support healthy aging, it’s often recommended to take it in the morning with a meal that contains healthy fats—such as nuts or avocados—to enhance absorption.

Read More: 8 Heart Healthy Supplements To Consider (and 2 To Avoid)

NMN

NMN supplements
Credit: Supplyside

NMN (Nicotinamide Mononucleotide) is currently regarded as one of the most exciting molecules in the world of anti-aging science. This isn’t just hype talk either, as NMN is a precursor to NAD+, a molecule considered vital for life and longevity. As we get older, our NAD+ levels plummet by more than 50% by middle age. This decline is associated with fatigue, inadequate cell repair, slowed metabolism, and age-related illnesses. NAD+ is needed for cellular energy production, DNA repair, and activation of longevity proteins called sirtuins. In mice trials, NMN has been demonstrated to reverse signs of aging in vascular, muscular, and brain tissue. While studies on humans are still in their early stages, some preliminary findings indicate that elderly people benefit from improved insulin sensitivity and muscle performance.

Read More: 13 Medications and Supplements That May Help Slow Brain Aging

Quercetin

quercetin
Credit: Wikipedia

Quercetin is a plant flavonoid naturally found in apples, capers, berries, and even green tea. It has been studied extensively for its broad-spectrum protective effects, particularly in conditions related to aging. Among its noteworthy properties is its ability to influence SIRT1, one of the same sirtuins activated by resveratrol. This connection to DNA repair, inflammatory regulation, and cellular resilience positions quercetin at the forefront of research aimed at slowing the aging process.

Quercetin works by neutralizing free radicals, which can damage DNA, proteins, and cellular membranes. This process decreases oxidative stress, which is a major contributor to aging. A study by Liu et al. (2021) shows how quercetin reduces oxidative stress. Furthermore, quercetin helps suppress inflammatory enzymes such as cytokines and COX-2, which play roles in chronic inflammation and aging-related diseases, as discussed in research by Villar et al. (2022).

In addition to its antioxidant and anti-inflammatory effects, studies have linked quercetin consumption with a reduced risk of cardiovascular disease, improved metabolic health, and even neuroprotection. A study by Di Pierro et al. (2016) found that quercetin improved cardiovascular health and lowered blood pressure in hypertensive mice. Moreover, research by Huang et al. (2020) suggests that quercetin may help protect the brain from neurodegenerative conditions, indicating its potential role in promoting cognitive longevity.

The Bottom Line On How To Slow Aging

supplements
Credit: Pixabay

While aging is a natural aspect of life, how we age is something we can control. By including morning supplements such as resveratrol, NMN, and quercetin into your morning routine, you could potentially strengthen your body’s natural defenses, increase cellular vitality, and promote healthier aging from the inside out. They do not provide fast results, but they may reduce inflammation, assist DNA repair, and improve your body’s response to stress and damage. Of course, supplements are most effective when combined with a healthy diet, regular exercise, and proper sleep. Consider them not as short solutions, but as part of an overarching plan for aging well and living longer.


 Disclaimer: This information is not intended to be a substitute for professional medical advice, diagnosis or treatment and is for information only. Always seek the advice of your physician or another qualified health provider with any questions about your medical condition and/or current medication. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.

Read More: Study Suggests Vitamin D Supplements May Help Alleviate Multiple Sclerosis Symptoms