Identifying a Specific Brain Circuit

Researchers at Weill Cornell Medicine have pinpointed a distinct neural pathway that plays a crucial role in anxiety. This circuit involves the metabotropic glutamate receptor 2 (mGluR2), a receptor that modulates neuronal activity. By focusing on this receptor within a particular brain circuit leading to the amygdala, a key center for emotion processing, they found that manipulating this pathway can reduce anxiety behaviors.