Potential Mechanisms and the Path Forward
The researchers theorize that F. prausnitzii uses the S-adenosyl-L-methionine cycle I pathway to influence dopamine and serotonin levels. These are neurotransmitters produced in the gut. The role of these neurotransmitters is to regulate how foods pass through your digestive tract. However, they can also make their way to the brain, resulting in an elevation in mood. F. prausnitzii bacteria is also linked to other health benefits, such as a lower inflammatory bowel disease risk. It has also been shown to help with obesity and even type 2 diabetes in animal studies. The researchers hope to see a clinical trial conducted next that would specifically focus on the link between citrus consumption and lower depression risk.
As evidence of a link between the gut and brain is uncovered, more researchers will start to explore this field. Finding affordable, easily obtainable treatments for depression is crucial if we wish to help the millions of people afflicted globally. Researchers are learning more about the role of the gut microbiome and its effect on the brain every day. This could open potential therapies that don’t rely on medications that often present their own range of side effects. Other foods that may be beneficial to gut bacteria are fiber-rich vegetables and fruits, as well as fermented foods. These foods help balance the gut which helps influence neurotransmitters like serotonin.
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