The diagnosis of stage 4 colon cancer in 21-year-old Brinlee Luster has sparked a conversation about the rising cancer rates in young people. While Brinlee experienced severe symptoms like abdominal cramping and fatigue, her twin sister, Mariela, didn’t show any signs of the disease. Their different experiences have led many to question why cancer is becoming more common in younger individuals, especially colon cancer. Dr. Mark Lewis, a gastrointestinal oncologist, offers his insights into the factors driving this troubling trend.
At first, doctors chalked up Brinlee’s symptoms to stress. But after insisting on more tests, Brinlee was diagnosed with stage 4 colon cancer. She began treatment right away, undergoing 30 rounds of chemotherapy. Now, after completing treatment, she is cancer-free, though her journey hasn’t been easy.
Mariela, who had no symptoms, decided to get a colonoscopy after hearing about her twin’s diagnosis. During the procedure, doctors found and removed precancerous polyps. Mariela credits Brinlee’s diagnosis with saving her life. Dr. Lewis believes that factors like genetics, lifestyle, and medication use are all playing a role in the increase of diagnoses.
The Link Between Antibiotics, Genetics, and Cancer Risk
One theory Dr. Lewis points to is the role of antibiotics in the rising cancer rates in young people. He believes that the overuse of antibiotics, especially in childhood, can disrupt the gut microbiome, increasing cancer risk later in life. Antibiotics alter the gut’s bacteria, and frequent use could weaken the body’s defenses against harmful substances, including cancer-causing agents. Though the Luster twins didn’t discuss their antibiotic use, Dr. Lewis’s theory suggests that common medications may have long-term risks.
The link between antibiotics and cancer is still being studied, but Dr. Lewis argues that overuse can make the body more vulnerable to cancer. If future research supports this, it could change how we approach cancer prevention and treatment.
Genetics also play a role in cancer risk. Though Brinlee’s family didn’t have a history of colon cancer, Dr. Lewis believes that genetic mutations can increase the likelihood of developing cancer. However, he emphasizes that genetics alone isn’t the only factor. Lifestyle choices, such as diet and exercise, and environmental exposures also contribute to cancer risk. This combination of genetics and environment may explain why more young people without a family history are being diagnosed with cancer. Even small genetic changes, when combined with environmental factors, can lead to early cancer development.

Lifestyle Choices, Stress, and the Importance of Early Detection
Dr. Lewis highlights how lifestyle choices impact the rising cancer rates in young people. Poor diets high in processed foods and low in fiber, combined with a lack of physical activity, increase cancer risk. Young people today are more likely to eat unhealthy foods and live sedentary lives, both of which contribute to higher cancer rates. Obesity, for example, is a proven risk factor for colon cancer. When combined with genetics, these lifestyle choices may be driving the rising number of cancer cases in younger people.
Brinlee’s diagnosis serves as a reminder of the importance of early detection. Colon cancer is often silent in its early stages, which makes it difficult to detect without testing. Regular screenings, such as colonoscopies, are vital, especially for people with a family history or other risk factors. In Mariela’s case, her decision to get screened after her sister’s diagnosis could have possibly saved her life.
Stress is another factor that might influence cancer risk. Though stress itself doesn’t directly cause cancer, it can weaken the immune system and increase inflammation, which may make the body more vulnerable to disease. Brinlee’s symptoms were initially written off as stress-related, but as her condition worsened, it became clear that stress wasn’t the main issue. Dr. Lewis advises managing stress through healthy habits like exercise, therapy, and maintaining a balanced lifestyle. Reducing stress not only improves overall health but may also lower the risk of developing cancer and other chronic diseases.
Raising Awareness and Changing Health Attitudes
Brinlee’s case highlights the need for a shift in how we think about health. Dr. Lewis’s theories provide a foundation for further research into the causes. While the connection between antibiotics, genetics, and lifestyle choices requires more study, the important takeaway is that early detection can make a big difference.
We need to raise more awareness about the risks of colon cancer and the importance of screenings. Being proactive about our health, getting regular checkups, and making healthy choices can help reduce cancer risk. Early detection, healthy habits, and understanding the risks may allow us to reverse the trend of rising cancer rates in young people.
By making these changes and focusing on prevention, we can better protect ourselves and future generations from cancer. Brinlee’s story is a reminder that cancer doesn’t only affect older adults—it can strike at any age. Early intervention and a greater focus on prevention can help save lives and combat the growing issue of rising cancer rates.
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