Pain

One of the early symptoms of the disease is a range of different bodily pains. Many patients experience unexpected and persistent pain that does not subside, eventually leading to a check-up that confirms the diagnosis. This pain can often come in the form of musculoskeletal pain that affects the patient’s ligaments, tendons, muscles, bones, or nerves. It can also present as neuropathic pain resulting from damage to the nerves. Patients can also experience dystonic pain that results in cramps and muscle spasms and central pain caused by the improper functioning of certain pathways that control brain sensations.