A household herb, rosemary, contains a potent compound that may combat neurodegenerative diseases like Alzheimer’s. A new study by The Scripps Research Institute highlights a treatment derived from rosemary and sage. This development offers hope for Alzheimer’s patients.
The institute engineered carnosic acid, a natural antioxidant with anti-inflammatory properties, into a stable derivative. The derivative form, called diAcCA, has shown incredible results in reversing memory loss and reducing neuroinflammation during tests conducted on mice. This amazing breakthrough opens up new, non toxic methods for tackling Alzheimer’s, a disease affecting over 6.9 million Americans and millions worldwide.
The Science Behind the Rosemary Compound for Alzheimer’s
Carnosic acid in its pure form cannot be given as a drug due to instability. Researchers solved this obstacle by synthesizing diAcCA, a stable derivative that remains stable until changed back into carnosic acid in the gut. This conversion process has shown a 20% higher rate of absorption into the bloodstream in this derivative form, compared to pure carnosic acid. This synthesized, stable form enables it to reach the brain within an hour.
The compound targets neuroinflammation, a major cause of Alzheimer’s progression. By activating the enzymes important for the body’s natural defenses, diAcCA boosts the body’s natural defenses against oxidative stress and inflammation. These processes cause synaptic loss and lead to cognitive decline. Notably, diAcCA not only treats inflammation but research has shown to improve memory and synaptic density in the brain.
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