Julie Hambleton

Julie Hambleton

November 17, 2024

Doctor Explains #1 Test That Can Best Predict Sudden Death From Heart Attack

Cardiovascular disease continues to be a major public health concern, affecting millions of individuals worldwide. However, a recent study supported by the National Institutes of Health (NIH) has uncovered a groundbreaking discovery that could revolutionize the early detection and prevention of cardiovascular disease in women. On top of that, there are a number of tests that can accurately predict your risk of a sudden heart attack, and one test in particular stands out among the rest.

Blood Test for Heart Attack Risk: The Study

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Detection of heart attack risk is crucial to prevention and early intervention. Recently, researchers discovered a blood test that can achieve this in women. Conducted by researchers at the National Institutes of Health, the study focused on assessing the predictive capabilities of a single blood test in determining the risk of cardiovascular disease in women. Over a span of 30 years, 27,939 female participants from the Women’s Health Study were monitored and provided blood samples for analysis. The researchers aimed to measure the levels of inflammation and lipids in the bloodstream, specifically focusing on C-reactive protein (CRP), low-density lipoprotein (LDL) cholesterol, and lipoprotein(a) [Lp(a)].

The Result

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The findings of this study, published in the New England Journal of Medicine and presented at the European Society of Cardiology Congress 2024, revealed significant insights into the correlation between these blood markers and the risk of cardiovascular events. Women with elevated levels of LDL cholesterol, Lp(a), and CRP were found to have a substantially higher associated risk of developing heart disease and stroke compared to those with lower levels. When all three markers were evaluated collectively, the risk of stroke and coronary heart disease significantly increased for participants with the highest levels.

What this means for your health

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These findings provide valuable information for healthcare providers and individuals looking to assess and mitigate their risk of cardiovascular disease. By recognizing the impact of inflammation and lipids on cardiovascular health, individuals can take proactive steps to monitor their blood markers and make necessary lifestyle changes to reduce their risk. Engaging in regular physical activity, adopting a heart-healthy diet, managing stress, and avoiding tobacco use are essential components of maintaining optimal cardiovascular health.

“These data should be a wake-up call for women,” saidsaid co-author Julie Buring, ScD, principal investigator of the WHS and an epidemiologist in the Brigham’s Division of Preventive Medicine. “Waiting until women are in their 60s and 70s to initiate heart attack and stroke prevention is a prescription for failure.”

Furthermore, the study highlights the importance of early detection and personalized treatment strategies. While LDL cholesterol can be managed with existing therapies like statins, screening for Lp(a) and CRP may require tailored approaches depending on individual risk factors and familial history of cardiovascular disease. Researchers are exploring new therapies and interventions to enhance treatment options for individuals with elevated blood markers.

“While we still need to focus on lifestyle essentials like diet, exercise, and smoking cessation, the future of prevention is clearly going to include combination therapies that target inflammation and Lp(a) in addition to cholesterol,” said lead author Paul Ridker, MD, director of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital.

Tests to Predict Risk of Sudden Heart Attack

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This new blood test, however, is not the only method of predicting future risk of heart attack. There are other methods that have high accuracy that doctors have been using for quite a long time now. Your doctor may order one of these tests if they think that you could be at risk for heart attack.

Electrocardiogram (EKG or ECG)

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The electrocardiogram is a widely-used test for examining the heart’s health by recording its electrical signals. It is a quick, easy, and relatively inexpensive procedure that provides valuable information about the heart’s activity. However, despite its widespread use and benefits, the ability of EKGs to predict the likelihood of a future heart attack is limited. According to the information provided, EKGs can only identify old heart attacks in about 48% of cases, rendering their predictive ability comparable to chance. This significant limitation underscores the need for additional tests with higher predictive accuracy to better assess the risk of sudden heart attacks.

Coronary Calcium Scan

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Another test commonly used to assess the risk of sudden heart attacks is the coronary calcium scancoronary calcium scan. This imaging test detects the amount of calcium build-up in the walls of the heart’s arteries, which can indicate the presence of atherosclerosis and a heightened risk of heart disease. A higher calcium score suggests an increased risk of future heart attacks, providing valuable insights into an individual’s cardiovascular health. The use of the coronary calcium scan allows physicians to identify individuals at higher risk and implement appropriate preventive measures such as lifestyle modifications and medical interventions to mitigate the potential for a sudden cardiac event.

The Bottom Line

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The discovery of a blood test that accurately predicts the risk of cardiovascular disease in women represents a significant advancement in cardiovascular research. By leveraging this knowledge and implementing preventive measures, individuals can empower themselves to safeguard their heart health and potentially prevent the onset of cardiovascular events in the future. Otherwise, the electrocardiogram (EKG or ECG) remains a valuable tool for assessing overall heart health. Its predictive limitations call for the incorporation of additional tests such as the coronary calcium scan to provide a more comprehensive evaluation of an individual’s risk of experiencing a sudden heart attack. By leveraging a combination of tests with higher predictive accuracy, healthcare providers can offer more personalized and effective strategies to prevent and manage the risk of fatal cardiac events.