Imagine feeling really drained and tired all the time, even after simply performing household chores. This is the daily reality for millions of individuals diagnosed with chronic fatigue syndrome. It is estimated that around 1.3% of the American population lives with this illness, yet many people remain undiagnosed. Not much is understood about the causes of this condition, or who is most at risk. However, it seems to be most common in women between the ages of 40 and 60. Let’s look at the most common symptoms, treatment options, and potentially beneficial natural remedies for chronic fatigue syndrome (CFS).
The Causes of Chronic Fatigue Syndrome

Researchers are still trying to figure out what causes chronic fatigue syndrome, however, they have come up with some theories. One theory is that it develops due to past bacterial and viral infections such as the Ross River virus, Epstein Barr virus, and Coxiella burnetti. The development of chronic fatigue syndrome has also been linked to immune system malfunction. Some studies have also revealed that individuals diagnosed with CFS struggle with cellular energy production. This can occur in muscle cells, potentially leading to common CFS symptoms, such as fatigue and muscle pain.
Another theory is that it develops as an abnormal response to stressful situations. When we find ourselves in physically or mentally stressful situations, our bodies release a hormone called cortisol. It is believed that some people may have lower-than-normal cortisol levels and stress can cause a flare-up of their immune systems. Some researchers believe that it is this inflammation that results in CFS. Other likely factors that influence the disorder’s development include genetic and environmental interactions. Many researchers agree that it is likely a combination of these factors in addition to the others that have yet to be uncovered.
Read More: 8 Signs You’re Suffering From Chronic Fatigue Syndrome
The Symptoms of Chronic Fatigue Syndrome

CFS symptoms often fluctuate unpredictably, improving or worsening over time. The most common symptom is severe exhaustion that doesn’t go away, no matter how much you rest. It is typically overwhelming and even performing the simplest of tasks becomes a big challenge. Maintaining a normal work or social life grows increasingly difficult for many people with this condition. Another symptom of CFS is restless sleep and insomnia, usually getting up feeling just as tired as before they went to bed. Many people also report suffering from “brain fog”, making it hard for them to think clearly or focus. Even holding a conversation or trying to read can often leave them feeling mentally exhausted.
People also often report experiencing pain in the joints and muscles without any apparent cause. Some individuals also grow sensitive to light, sound, and touch. Another symptom of CFS is that people experience dizziness, blurry vision, and lightheadedness when standing up from a seated position. Some people also experience digestive issues, such as IBS, nausea, and bloating. Even performing the most basic of activities can lead to an energy crash that can last anywhere from a few days to weeks, known as Post-Exertional Malaise.
Chronic Fatigue Diagnosis

At present, there is no test for CFS and the doctors typically base their diagnosis on the patient’s symptoms. Your doctor will first examine your medical history and then perform a physical exam to rule out other potential health issues. For instance, they may take blood samples to check your thyroid levels and blood count to rule out potential causes for the symptoms such as a thyroid imbalance or anemia. They may also take lung X-rays or ECG readings of your heart if you are experiencing any palpitations or difficulties breathing. If they can’t find any other reason for your symptoms, then your doctor may suspect that CFS is the cause.
A patient will typically display three common symptoms before a doctor will make a CFS diagnosis with confidence. The first symptom is at least six months of fatigue that decreases one ability to perform everyday tasks. The second one is that the symptoms worsen after physical or mental activity. The third symptom is that the person has issues with their sleep and feels tired upon awakening. Additionally, they must also either have issues with their focus or symptoms that worsen after trying to stand up. If the symptoms fit this criteria, then a doctor will diagnose the ailment as CFS.
CFS Treatment Options

Until we know for sure what the causes of CSF are, it is almost impossible to create definitive treatments. However, there are certain strategies that assist in the alleviation of symptoms, allowing patients to perform daily activities without great difficulty. One strategy involves activity management. By taking note of the specific activities that lead to fatigue, patients can learn to not overexert themselves during that activity or avoid it altogether. Keeping a journal of these fatigue-causing triggers allows patients to try to find a balance between periods of rest and activity.
The next strategy help patients learn to cope with symptoms that cannot be alleviated. Known as cognitive behavioral therapy, it is helpful in treating the depression and anxiety that often accompany chronic fatigue syndrome. Depending on which symptoms the patient is experiencing, some people find certain medications beneficial, such as painkillers and antidepressants. Since this condition is so complex, presenting such a large range of potential symptoms, every strategy needs to be customized to meet the patient’s personal requirements.
Emerging Studies on CFS and Mitochondrial Dysfunction

In order for your body to have optimal energy levels, you need to have healthy mitochondria. When your body’s ATP levels are low, this can lead to feeling fatigued and drained. While we have much to learn about how this condition develops, it is thought that mitochondrial dysfunction may exacerbate the symptoms. Therefore, finding ways to improve mitochondrial function would result in an increase in ATP levels, which means there would be more energy available for the cells to use.
One study from 2021 examined how well the energy-producing parts of blood cells worked in older adults, both with and without fatigue. The researchers found that those with fatigue had lower energy production in their blood cells, struggled with daily activities, and were more depressed. Another study likewise found that when compared to a control group without CFS, CFS patients displayed altered mitochondrial metabolism along with a reduction in capacity to meet cellular energy demands.
Consuming the right nutrients helps support mitochondrial function and your overall health. Adding colorful fruits and vegetables to your diet helps ensure that you get all the anti-inflammatory compounds and antioxidants that you require to boost the growth and functioning of your mitochondria. Some research suggests that intermittent fasting may also be beneficial to certain individuals if done in a manner that suits their personal nutritional strategy.
Studies on CoQ10 and NADH For Chronic Fatigue Syndrome

CoQ10 is a dietary enzyme that has also been studied for its role in maintaining mitochondrial health. Imbalances of CoQ10 and NADH have been observed in people with CFS. Could taking NADH and CoQ10 supplements help improve symptoms of chronic fatigue syndrome? That is the question that the researchers of a 12-week study attempted to answer. For the study, 207 individuals diagnosed with CFS were given Coq10 and NADH supplements or a placebo. They wanted to find out if there were any changes in fatigue levels, sleep quality, and health quality.
The results revealed small cognitive improvements in terms of fatigue, but no other major improvements to general fatigue other than that. Compared to the participants who took the placebo, the others noted a marked improvement in sleep duration and efficiency. When it came to quality of life, the group who had taken the supplements reported an improvement in physical function and pain compared to the placebo group. Other supplements that have proven promising include l-carnitine, magnesium, probiotics, and s-adenosyl Methionine. Let’s now take a look at some other natural ways to deal with chronic fatigue syndrome.
Natural Ways to Manage Chronic Fatigue Syndrome

While there is no cure for this condition, there are approaches that can potentially help increase and support energy levels and reduce inflammation. We already mentioned nutritional support above, such as taking l-carnitine, magnesium, probiotics, and s-adenosyl Methionine. Other supplements and vitamins you should consider are vitamin B12 and B complex, which are needed for energy production and proper nerve functioning. Consuming omega-3 fatty acids is also beneficial and can be found in foods such as walnuts, flaxseeds, and fish. When it comes to diet, we already mentioned eating colorful fruits and vegetables. However, you should also eat lean proteins, whole grains, and healthy fats.
Be sure to avoid foods with too many artificial additives, sugar, and highly processed products. Dehydration can also add to fatigue, so make sure that you stay hydrated by drinking enough water and herbal teas. There are also several herbal supplements that you can try, such as ashwagandha, which is known to help the body manage stress and improve energy levels. Another supplement that may boost mitochondrial function is Rhodiola rosea. Ginseng is another popular supplement known for its energy-enhancing qualities. Adding ginger and turmeric to your diet may also be useful, as they may help reduce certain symptoms due to their anti-inflammatory properties. When it comes to CFS, managing your sleep and stress levels is very important.
Try and maintain a consistent bedtime and avoid screens before going to bed.

Try a relaxation technique, such as yoga or deep breathing. This can help lower the stress which can often worsen symptoms. During the day, doing gentle exercises, such as stretching and walking may help improve circulation without overexerting yourself. It’s also important to consider your gut health, which has been linked to energy levels and immune system function. An imbalance of gut bacteria can result in increased inflammation and a drop in energy levels. You can support your gut health by eating fermented foods and probiotics. Some people also find that some symptoms are alleviated by reducing the intake of food that they have intolerances to, such as dairy and gluten. Acupuncture has also shown some promise in relieving pain and fatigue in some chronic fatigue syndrome patients.
The Mental and Emotional Impact of Living With CFS

Living with chronic fatigue disorder has an impact not just on the physical, but also on one’s mental and emotional health. Many people with CFS experience considerable anxiety and depression as a result of their inability to do all the things they once enjoyed. The unpredictable nature of symptoms can make it rather difficult to make social plans or sustain relationships. Some people experience shame, particularly when they are unable to meet family or job obligations. Constant fatigue and cognitive decline may cause feelings of helplessness, loss of identity, and even self-doubt. Many people with CFS miss their previous lifestyles and wish they could just feel normal again.
A lack of understanding from others may lead to isolation, therefore it’s essential to find circles of support. Seeking therapy, joining support groups, or simply talking with friends and family can all help manage the psychosocial effects of chronic fatigue syndrome. Mindfulness activities, creative hobbies, and journaling can all help people process their emotions when dealing with the symptoms of CFS. Setting achievable goals and celebrating minor victories can potentially help increase a person with CFS confidence and resilience.
The Bottom Line on Chronic Fatigue Syndrome

Chronic Fatigue Syndrome is a complex illness that affects millions of individuals worldwide. Infections, immunological dysfunction, or mitochondrial abnormalities are thought to be potential causes. Extreme fatigue, mental fog, joint pain, and stomach difficulties are among the symptoms that typically make daily tasks feel overwhelming for people living with CFS. There is no cure, however, treatment options can help alleviate symptoms.
Lifestyle modifications, cognitive therapy, vitamins, and pacing techniques have all been shown to be beneficial to some patients. Proper nutrition, stress reduction, and adequate sleep promote general well-being and could help alleviate many of the symptoms. Emotional wellness is just as crucial, as depression and anxiety are common in CFS patients. Raising awareness and promoting research may help us better understand chronic fatigue syndrome over time. Managing this syndrome takes a lot of self-care and patience. However, by applying the right strategies, you can learn to manage CFS in a natural way.
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