Catherine Vercuiel

Catherine Vercuiel

March 23, 2025

Could a Common STI Be Linked to Dementia? Experts Raise Concerns.

Recent findings from Uppsala University in Sweden have sparked a conversation in the medical community. Researchers are examining how a certain sexually trasmitted disease can indirectly affect brain health later in life. It suggests that individuals with herpes may face twice the risk of developing dementia. Those without the virus appear to have better outcomes. This revelation has many health professionals taking notice. It calls for a closer examination of the relationship between herpes and long term cognitive health.

Close-up of oral herpes lesion on a person's lip, showing the characteristic blisters associated with HSV-1 infection. Research links this common virus spread through sexual practice to increased dementia risk later in life.
Credit: Pexels

The herpes virus affects billions of people. Many don’t know they have it. The virus can spread through intercourse and other close contact. Most people think herpes just causes sores, but it might also harm brain health years later.

A key study tracked 1,000 seniors for 15 years. The work backs up past hints of a link between herpes and dementia. This adds to growing proof that common bugs might lead to brain problems years later. Medical professionals are increasingly studying herpes and dementia connections to understand preventive measures. “We still do not have answers regarding causal mechanisms of this association, whether the virus causes the disease or if there is an indirect link,” says a lead author of the study.

Understanding Herpes and Dementia: The Numbers

Dementia affects more than 55 million people globally. Nearly 10 million new cases are diagnosed each year. By 2030,experts predict this number will reach 78 million. The numbers are staggering. These statistics make any potential risk factor worth investigating. Oddly enough, something as universal as how we physically connect with others might be playing a role in this cognitive health puzzle.

Herpes is remarkably common. According to the World Health Organization, approximately 64% of people under age 50 globally have herpes simplex virus type 1 (HSV-1) infection, typically transmitted through oral contact like kissing. Meanwhile, about 13% of people aged 15-49 have herpes simplex virus type 2 (HSV-2), usually transmitted through intimate physical contact. Both forms spread through everyday forms of human connection that most would consider normal parts of intimate relationships.

Read More: Bell’s Palsy: What Causes It, and Symptoms to Look Out For

How Might Herpes Affect Brain Health?

Brain scan showing cross-section of neural tissue that may reveal changes associated with dementia. Recent studies suggest certain sexual practices that transmit viruses like herpes may influence dementia risk in aging populations.
Credit: Pexels

Dementia occurs when damage to brain cells interferes with their ability to communicate with each other. Different types of dementia affect specific regions of the brain. For instance, Alzheimer’s disease typically begins in the hippocampus, the brain’s center for learning and memory. While researchers are still investigating the exact mechanism, the oral form of herpes appears to be the primary concern regarding dementia risk.

“The main culprit seems to be HSV-1, which commonly infects the oral region,” researchers explain. “However, HSV-1 and HSV-2 can both infect either the oral or the genital region. This is important to have in mind when these studies are conducted.” This shows that how we touch and kiss might affect brain health in ways we never thought about before. A doctor warns us to be careful. “There could be important differences between those with or without herpes simplex virus status and those who developed dementia or not,” experts note. “It is difficult to control all confounders that have been traditionally associated with dementia.”

Should You Be Concerned?

If you have herpes, should these findings worry you? Experts suggest a measured response. “Given how common herpes virus infection is in young people, I would not let this study concern you too much,” Dr. Gandhi notes. She points out that the prevalence of HSV is very high (up to 80% in some populations), while dementia rates are considerably lower.

Traditional risk factors for dementia include diabetes, hypertension, and smoking. Managing these conditions remains crucial for brain health regardless of herpes status. Health experts have some tips for people with herpes. Getting tested and treated with virus drugs may help. Some studies show good news: herpes drugs might cut dementia risk for people with symptoms. The link between kissing, virus spread, and brain health is both simple and tricky, like solving a puzzle with some pieces hidden. We need more drug tests to be sure of these early findings.

Herpes and Dementia: What to Know About Safety

We still need close bonds with others, while science works on these health links. No one says to stop intimate activities. But we can be smarter about how viruses spread. While herpes has no cure, we can cut risks and treat symptoms: Antiviral medications like acyclovir, famciclovir, and valacyclovir can decrease the severity and duration of outbreaks. For frequent recurrences, daily suppressive therapy may be recommended.

For pain management, over-the-counter options include paracetamol, naproxen, or ibuprofen. Topical numbing agents like benzocaine and lidocaine can provide localized relief. Certain triggers can reactivate the herpes virus, including:

  • Illness or fever
  • Sun exposure
  • Menstrual periods
  • Physical injury
  • Emotional stress
  • Surgery

To cut the risk of virus spread through close contact, doctors suggest:

  • Talk openly with partners about health
  • Avoid kissing and sex when you have sores
  • Use condoms
  • Don’t share cups, lipstick, or food items
  • Know that both kissing and sex can spread the virus

The Bigger Picture: Brain Health and Sexual Health

Silhouette of a couple kissing against sunset background, representing intimate contact that can transmit the herpes virus. Everyday expressions of affection like kissing may have unexpected connections to long-term brain health.

This work shows us new links in health. The viruses we spread when we touch or kiss might harm our brains years later. Doctors need to think about love life and brain health as parts of the same big picture. Isn’t it odd that the hugs and kisses we love might sometimes hurt us later? While the link between herpes and dementia requires further investigation, it reminds us that brain health involves multiple factors across our lifespan. This research doesn’t suggest avoiding normal human connection, but rather being mindful about health in all relationships.

Read More: Grieving Mother Wished She Spoke Up When A Family Member With Herpes Kissed Her Newborn