Julie Hambleton

Julie Hambleton

June 4, 2025

Ozempic for Weight Loss and Diabetes: How It Works, and What Can Go Wrong

Unless you’ve been living on a far-off island with no internet connection or television service, you’ve probably heard of Ozempic. It’s the drug that started out as a diabetes drug, until it was discovered that it is impressively effective for weight loss. A few celebrity endorsements later and bam – Ozempic for weight loss was all the rage. As always with pharmaceuticals, this drug does not come without side effects, and as more and more people are taking it, we’re seeing an increasing number of these unwanted effects. Some of these being discovered are actually quite dangerous. If you are already taking Ozempic for weight loss, considering taking it, or know someone who is, this is all the information that you need to be aware of.

How Ozempic Works

Valparaiso, IN USA December 13, 2023:  Ozempic pen and box close up
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Ozempic is a GLP-1 receptor antagonist medication. This is a very medical way of saying that it is a medication designed to regulate blood sugar levels by doing two things: Stimulating the release of insulin while simultaneously inhibiting glucagon secretion. This combination effect helps people with Diabetes to control spikes in blood sugar, particularly after meals. As we have since learned, this can also aid in weight management.

What Ozempic is Used For

Diabetic patient using insulin pen for making an insulin injection at home. Woman control diabetes. Diabetic lifestyle
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Ozempic was developed for those with type 2 diabetes. It is primarily prescribed to help these patients improve glycemic control. This is what the medication was invented for, and for a long time, was the primary focus. That is, until it was discovered that Ozempic can also lead to weight loss, potentially reducing the risk of cardiovascular disease in patients with diabetes. As we know, these weight loss effects have, in the last year, taken social media by storm.

Why Ozempic is So Expensive

Raleigh, NC - USA - 08-15-2024: A cellphone with the Ozempic website displayed on the screen and a twenty dollar bill
Source: Shutterstock

While it may seem like everyone you see online is taking Ozempic, the reality is that this is actually a really expensive medication. Novo Nordisk, the pharmaceutical company that manufactures and sells Ozempic, says that the high cost is because of its ’innovative and effective mechanism of action’, in addition to all the research and development involved to bring the medication to market. Finally, they site the production process and the need for ongoing clinical trials as major contributing factors to the overall cost of the medication.

Who Makes It

Novo Nordisk advertising flags and logo on facade, Danish pharmaceutical healthcare giant Novo Nordisk AS, production innovative drugs, obesity treatment Ozempic, Mainz, Germany – June 15, 2024
Source: Shutterstock

As already mentioned, Ozempic is manufactured by Novo Nordisk, a pharmaceutical company with a long-standing reputation for producing diabetes medications, with over 90 years of experience in the field of diabetes care. The company has been recognized for its focus on research and development, with a particular focus on finding newer, more effective treatment options for individuals with diabetes. A leader in diabetes research, they have contributed significantly to advancements in diabetes treatment as well as patient care.

Read More: Ozempic May Reverse Early Signs of Disease Behind 2M Deaths a Year

Ozempic and Weight Loss

Qawra, Malta - 21.08.2024 - Semaglutide, Ozempic. Drug for diabetes. Choosing ozempic intead of healthy food. High quality photo
Source: Shutterstock

It was first discovered that Ozempic was potentially impactful for weight loss during clinical trials in 2017, shortly after the FDA approved it for the treatment of type 2 diabetes. The researchers observed that the patients receiving Ozempic experienced significant weight loss as a side effect. They considered this a positive outcome, albeit an unexpected one. It led to further research on the potential of Ozempic as a weight loss aid in addition to its use as a diabetes medication. This discovery, of course, garnered the attention of the medical community, as well as among individuals seeking to lose and/or manage their weight.

The drug became all the rage on social media, with some influencers and celebrities endorsing it, while many others were speculated to be using it due to their seemingly dramatic body transformations. This, naturally, led to many people wondering if they, too, could use Ozempic to lose weight. The key when using Ozempic for weight loss is to work with your doctor to find the right dosage. This will require consideration of many individual factors, including medical history, current health status, and treatment goals. If your doctor does prescribe you Ozempic, they will monitor your response to the initial doses – your overall health, any existing medical conditions, as well as lifestyle habits, dietary habits, and physical activity levels. While it may seem like Ozempic is the magic pill to weight loss that many have dreamed of, the truth is that lifestyle changes will still be necessary in order to reach your goals and maintain them. The effectiveness of Ozempic will vary among individuals. Optimal dosages should be determined by a qualified physician and strictly adhered to.

Can Ozempic Cause Cancer?

Lavender ribbon. World cancer day concept.
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No, there is currently no research or clinical trials that show any direct links between Ozempic and an increased risk for cancer. That being said, Ozempic does have potential risks and side effects, just like any pharmaceutical does. It is highly important for individuals taking this medication to be aware of and report any unusual symptoms or changes in their health that they may experience to their healthcare provider. Having open and informed conversations with your doctor about the medications you are on and how you are feeling on them is the only way that they can determine your safety and whether or not there is a problem. Make sure that you have a clear understanding of the risks of any and all prescribed medications, their potential side affects, as well as your individual health circumstances and any associated risks.

Ozempic Face

ozempic face
Source: Cleveland Clinic

Ozempic Face is a term that has been used to describe one particular side effect of the medication. This is a phenomenon where individuals begin to notice changes in the appearance of their face. More specifically, it is the loss of the subcutaneous fat in the cheeks and around the eyes. This is called facial fat loss or facial lipoatrophy and can lead to a sunken or hollowed appearance in the face. Not everyone experiences this side effect, but it is important to be aware of the possibility and discuss concerns with your healthcare provider. You can also monitor your face to ensure timely intervention before the problem becomes bigger than it needed to be.

Other side effects of Ozempic can include nausea, diarrhea, constipation, stomach pain, and vomiting. The risk of these is particularly high in the initial stages of treatment. Usually they will subside as the body adjusts to the medication. If you are at all concerned, speak with your doctor. They can change your dosage or simply determine that this is not the right medication for you.

Read More: New Ozempic Side Effect Sparks Growing Concern Among Users

Ozempic Side Effects in Females

worried pregnant woman concerned and anxious woman in pregnancy overthinking worrying about pregnancy problem Pregnancy depression Mental health concept
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The side effects that women experience while using Ozempic don’t differ wildly from men. Clinical trials and real-world use show that the most common side effects remain the same: Nausea, vomiting, diarrhea, and gastrointestinal discomfort, primarily. There have been some concerns raised about whether or not Ozempic might negatively impact reproductive health or pregnancy outcomes. It is important for women using or considering Ozempic to have open conversations with their doctors about these concerns. As always, women who are looking to become pregnant soon or those who are already pregnant or breastfeeding won’t be advised to take this medication.

Study Findings on Ozempic Side Effects

Prague, Czech Republic - July 10 2024: OZEMPIC box of medication with SEMAGLUTIDE active substance by NOVO NORDISK, used for treatment of type 2 diabetes and weight loss.
Source: Shutterstock

A study published in Nature Medicine investigated data from over 2 million individuals with diabetes who were prescribed GLP-1 receptor agonist medications like Ozempic. While the researchers noted a reduction in the risk of 42 health conditions ranging from dementia to certain types of cancer, the results weren’t all positive. The research also found an increased risk of 19 negative health outcomes, including kidney damage and pancreatitis.

Read More: What is ‘Ozempic Finger’? Users Complain About Little-Known Side Effect of Popular Drug

Pancreatitis and Kidney Damage Risk on Ozempic

Chronic kidney disease, doctor with model for treatment urinary system, urology, Estimated glomerular filtration rate eGFR.
Source: Shutterstock

It is important to note that the likelihood of developing pancreatitis or suffering kidney damage while taking GLP-1 drugs like Ozempic is still generally considered low. Research suggests that the risk of pancreatitis is less than one percent. Cases of kidney damage also seem to be rare and have mostly been reported through isolated instances.

Managing Side Effects of Ozempic

Woman Suffering With Morning Sickness In Bathroom At Home
Source: Shutterstock

There are ways to mitigate the previously mentioned side effects. Your doctor will generally recommend that you stay hydrated, consume smaller meals, and avoid foods that are processed, high-fat, and/or made of refined carbohydrates. In general, it comes to eating better and practising a healthy lifestyle. Not only will it improve your success on Ozempic, but it will also help to mitigate its side effects.

Ozempic Alternatives

Barcelona, Spain - October 8, 2024: Packaging box and pen of Wegovy, semaglutide injectable for weight loss. Translation: Solution for injection in pre-filled pen. Subcutaneous use. Once a week.
Source: Shutterstock

Despite what it may seem like, Ozempic is the only medication out there that does what it does; there are actually other medications that offer similar benefits. Other options include Mounjaro, Tirzepatide, Wegovy, Alli, Xenical, Saxenda, and Semaglutide. Which one you choose will depend on your individual needs, preferences, and reactions to the medications. It will also depend on whether you are using the drug for diabetes management or only for weight loss. If you are switching from one medication to another, however, you must do so with the help and supervision of your doctor.

  • Ozempic to Mounjaro Conversion: These two medications function in different ways, meaning that switching from Ozempic to Mounjaro or vice versa must be carefully managed by your doctor. Follow their guidance strictly for best outcomes.
  • Are Ozempic and Tirzepatide the Same: Ozempic and Tirzepatide both belong to the same class of GLP-1 receptor agonists. That being said, they differ in dosing, efficacy, and potential side effects. Tirzepatide is an active ingredient, vs Ozempic is a brand name. Be sure to have an in-depth conversation with your doctor about the details and distinctions of each one, so you can make informed decisions. 
  • Are Ozempic and Semaglutide the Same: Semaglutide is also a GLP-1 receptor agonist, but it is still a different medication than Ozempic. This means that it has its own distinct formulation a dosing regimen. Again, be sure that you fully understand each medication, how it works, the dosing, and potential side effects before saying yes to either. 

Read More: Exploring Reports of Tooth Issues Linked to Ozempic Use

Ozempic with Insurance

New York, USA - 18 March 2021: Medicaid.gov company logo icon on website, Illustrative Editorial
Source: Shutterstock

Ozempic is expensive, but we’ve already covered that. Of course, if you have health insurance, it becomes much more accessible. But what if you don’t? All may not be lost. Depending on your situation, there are some potential options for you to explore. It is important to note that some options may only be available to you if you have diabetes, versus a prescription for weight loss alone. The important thing here is to work with your healthcare provider to find a financial solution that best suits you and your needs.

  • Ozempic Near Me Without Insurance: There are financial assistance programs available for those without insurance coverage for Ozempic. These can be offered by the manufacturer or organizations supporting diabetes management. You will have to do some research to determine which of these is available to you.
  • Ozempic with Medicaid: Medicaid coverage may be available for Ozempic, depending on a variety of factors. These include individual eligibility criteria and state regulations. You will need to check with your healthcare provider or directly with Medicaid authorities for information specific to your situation.

The Bottom Line

Happy curvy African woman doing jogging and workout routine while listening music with wireless headphones outdoor
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Ozempic has taken the United States by storm, being touted on social media as the “magic bullet to weight loss” that we’ve all been waiting for. The reality is that it is much more complex than that. It is primarily for diabetes management, and may or may not work for everyone. There are side effects, and potentially ones that we don’t know about yet. On top of all it, whether for diabetes management or weight loss, you still have to incorporate lifestyle changes in order to see lasting results. At the end of the day, if you are going to have to clean up your diet, improve your sleep routine, and start exercising regularly anyway, why not start with that first? Then, if your health parameters aren’t changing, speak to your doctor about help via medication. Ozempic has been a game-changer for many people’s health, but it can’t be a replacement for living more healthfully. 


 Disclaimer: This information is not intended to be a substitute for professional medical advice, diagnosis or treatment and is for information only. Always seek the advice of your physician or another qualified health provider with any questions about your medical condition and/or current medication. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.

Read More: Could Ozempic Be Causing Sudden Blindness? New Research Suggests a Link