Sean Cate

Sean Cate

July 20, 2024

Which Blood Type is The Rarest? Here Are The Least to Most Common Blood Types

Understanding blood types is crucial for various medical procedures, including transfusions and organ transplants. Blood types are classified based on the presence or absence of certain antigens on red blood cells. Here’s a detailed look at the eight main blood types, from the least to the most common, and a special mention of the rarest blood type in the world.

O-Positive (O+)

vials of blood
Credit: Pexels

Prevalence: 37.4% of the population
O-positive is the most common blood type, making up 37% of the U.S. population. It is found in 47% of African Americans, 53% of Latino Americans, 39% of Asians, and 37% of Caucasians.1 O+ blood can be given to any positive blood type, which is the least rare.

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A-Positive (A+)

A blood type
Credit: Pixabay

Prevalence: 35.7% of the population
A-positive is the second most common blood type. It occurs in 33% of Caucasians, 24% of African Americans, 27% of Asians, and 29% of Latino Americans. This type can donate to A and AB positive blood types.

B-Positive (B+)

needle of blood in a doctors hand
Credit: Pexels

Prevalence: 8.5% of the population
B positive is less common than A or O blood types but is still significant. This blood type can donate to B and AB blood types and receive from B and O blood types. As far as rare blood types go, B-Positive is rare but not quite THAT rare.

O-Negative (O-)

O blood type
Credit: Pixabay

Prevalence: 6.6% of the population
O negative is known as the universal donor type because it can be given to patients of any blood type in emergencies. However, only 7% of the U.S. population has O- blood.2 This type is crucial for trauma patients and newborns.

A-Negative (A-)

blood flowing through an artery
Credit: Pixabay

Prevalence: 6.3% of the population
A negative blood type is somewhat rare. It is found in 6% of Caucasians, 2% of African Americans, 0.5% of Asians, and 2% of Latino Americans. People with A- blood can donate to A and AB blood types.

AB-Positive (AB+)

cluster of blood cells
Credit: Pixabay

Prevalence: 3.4% of the population
AB positive is rare but more common than AB negative. AB+ individuals are universal plasma donors and can receive red blood cells from any blood type, making them universal recipients.

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B-Negative (B-)

Blood being tested on a slide
Credit: Pixabay

Prevalence: 1.5% of the population
B negative blood type is uncommon and is found in 2% of Caucasians, 1% of African Americans, 0.4% of Asians, and 1% of Latino Americans. This blood type can donate red blood cells to both B-positive and B-negative recipients.

AB-Negative (AB-)

AB Blood type
Credit: Pixabay

Prevalence: Less than 1% of the population
AB negative is the rarest of the eight main blood types. This type occurs in only 0.6% of the U.S. population and is even rarer globally. People with AB- blood can receive red blood cells from all negative blood types but can only donate to other AB-negative or AB-positive individuals.3

The Rarest of Them All: Rhnull (Golden Blood)

Mysterious mystical heroine with golden drops on her face, golden tears and blood, fantasy art. Portrait of a beautiful elegant woman in mystical art makeup
Source: Shutterstock

Prevalence: Less than 1 in 6 million people
Rhnull, also known as golden blood, is the rarest blood type in the world. Individuals with Rhnull blood lack all Rh antigens on their red blood cells. This type is only found in about 40 people in the world are known to have it.4 Rhnull blood is extremely valuable for transfusions in individuals with similarly rare blood types.

Why Rare Blood Types Matter

Leukocyte poor pack red cell in transfusion bag on a tray inside blood bank.Label as O Rh plus.Rare blood group prepares for donation or therapy of anemia patient in hospital.Many plastic bags.
Source: Shutterstock

Rare blood types are crucial for certain medical treatments. For example, the Ro subtype, which is common among Black people, is vital for treating sickle cell disease. Demand for this subtype is increasing annually by 10-15%. Blood donations from people with rare types can save lives, especially for those requiring frequent transfusions or specific antigen matches.

Conclusion

Blood donation wheel
Credit: Pixabay

Knowing your blood type is essential for medical emergencies and treatments. The rarity of certain blood types emphasizes the importance of diverse blood donations. Whether you have a common or rare blood type, your donation can make a significant difference in someone’s life.

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Sources

  1. What is the rarest blood type? Here is the least common of the eight blood types.” USA Today. March 24, 2024.
  2. What are the rarest and most common blood types?Medical News Today. Danielle Dresden. January 31, 2024.
  3. Blood
  4. What is the rarest blood type?Medical News Today. Zawn Villines. October 10, 2023