hand holding a bottle of Tylenol
Sean Cate
Sean Cate
March 5, 2024 ·  3 min read

Doctor’s health warning to anyone who takes Tylenol on a regular basis

As one of the most commonly used painkillers worldwide, Tylenol, also known as paracetamol or acetaminophen, has long been touted as a safe and effective option for managing chronic pain. However, recent research has unveiled concerning implications for those who rely on this drug as part of their daily routine.1

Uncovering the Dangers of Tylenol

Arecent study conducted by the University of Edinburgh sheds light on potential risks associated with long-term Tylenol use, particularly for those with high blood pressure. The study, published in Circulation, revealed that regular Tylenol intake could lead to a significant increase in blood pressure, which would increase the risk of heart disease and stroke.

The study involved 110 patients with a history of high blood pressure who were prescribed one gram of Tylenol four times a day or a placebo for two weeks. The results were striking: participants who took Tylenol experienced a notable rise in their blood pressure levels compared to those who received the placebo.

These findings have significant implications for healthcare providers and patients alike. Principal Investigator Professor David Webb emphasized the importance of adopting a cautious approach when prescribing Tylenol for chronic pain management. He recommended starting with the lowest effective dose and closely monitoring blood pressure levels in individuals with hypertension.2 This is, of course, the best medical practice the it comes to drug use anyways; the lowest effective dose should always be what is strived for in medicine to avoid both overuse (and therefore over-reliance) and potential medicinal buildup in a patient’s system. 

Read More: 8 Dangerous and Deadly Drug Combinations

Implications for Patient Care

While Tylenol may offer temporary relief from pain, the potential cardiovascular risks associated with its long-term use underscore the importance of weighing the benefits against the potential costs. Professor James Dear echoed this need for doctors and patients to carefully consider the risks and benefits, particularly for individuals at risk of cardiovascular disease.

For individuals dealing with hypertension or anyone with an increased risk of heart disease or stroke, the findings of this study may warrant a reevaluation of your long-term Tylenol prescriptions. The research team emphasized the importance of exploring alternative pain management strategies and conducting regular reviews of medication regimens to ensure patient safety.3

In light of these findings, patients who rely on Tylenol for chronic pain management may have valid concerns about their medication intake. Dr. Iain MacIntyre reassured patients that the occasional use of Tylenol for isolated headaches or short bouts of pain is unlikely to pose any significant risk.

Looking Ahead 

As the medical community grapples with these implications, further studies are needed better to understand the long-term effects of Tylenol on cardiovascular health. Two weeks is by no means a long-term study, but considering how noticeable the differences are, it most certainly warrants further study. In the meantime, healthcare providers must prioritize patient safety and advocate for informed decision-making when prescribing pain medications.

The University of Edinburgh’s study serves as a wake-up call for healthcare providers and patients, highlighting the potential risks associated with long-term Tylenol use. By staying informed and prioritizing patient safety, we can work towards safer and more effective pain management strategies for individuals living with chronic conditions.

Read More: The Medications That Change Who We Are


  1. Regular paracetamol use linked to higher blood pressure.” BHF. Lisa Jones. February 7, 2022.     
  2. AHA Journals
  3. Regular paracetamol use linked to raised blood pressure.” The University of Edinburgh
  4. “Doctor issues warning to anyone who takes paracetamol regularly” The Indpendent