Julie Hambleton
Julie Hambleton
October 2, 2023 ·  4 min read

From Pain Relief to Sleep: 6 Benefits of Wild Lettuce

Have you ever heard of Wild Lettuce? No, this is not just salad greens growing naturally in forest without human intervention. This is a specific plant that has been used for centuries for various healing properties, including pain and sleep problems. This plant isn’t all good news, however – there are some potential dangers to consuming it. This is everything you need to know about Wild Lettuce.

What is Wild Lettuce?

Lactuca virosa blooming in summer garden.
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Wild Lettuce, scientifically known as Lactuca virosa, is a biennial plant native to Britain, Europe, and northern parts of Iran. It is also commonly found in North America. Often referred to as “opium lettuce” or “lettuce opium,” Wild Lettuce has a long history of use as a natural remedy for various ailments. The herb contains lactucarium, a milky sap that possesses sedative and analgesic properties.

6 Benefits of Wild Lettuce

The most well-known benefits of wild lettuce are pain relief and as a sleep aid. There are, however, other benefits beyond that. These are six of the potential benefits of this plant.

1. Pain Relief

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One of the most well-known benefits of Wild Lettuce is its potential as a natural pain reliever. The lactucarium found in the plant acts as a mild analgesic that helps alleviate conditions like headaches, muscle pain, menstrual pain, and arthritis. Wild lettuce is also a diuretic, which means that it can help alleviate fluid retention and reduce swelling. (1, 2)

2. Sleep Aid

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Wild Lettuce has been traditionally used as a sleep aid. Its sedative properties can help calm the nervous system, reduce anxiety, and promote better sleep. By inducing a relaxed state, it may also improve the quality and duration of sleep.

3. Respiratory Support

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Wild Lettuce has been used for respiratory issues such as asthma and bronchitis. It acts as a mild expectorant, helping to clear congestion and soothe coughs. (3)

4. Anxiety and Relaxation

Relaxed serene pretty young woman feel fatigue lounge on comfortable sofa hands behind head rest at home, happy calm lady dream enjoy wellbeing breathing fresh air in cozy home modern living room
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Due to its calming effects, Wild Lettuce is often used to manage anxiety and promote relaxation. It can help reduce feelings of restlessness, nervousness, and tension.

5. Digestive Aid

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The herb possesses mild digestive properties and has been used to treat digestive disorders such as indigestion, bloating, and flatulence. It can also act as a gentle laxative.

6. Migraine Relief

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Wild Lettuce may help alleviate migraines and reduce the frequency of headache attacks. Its analgesic properties, along with its ability to relax muscle tension, contribute to its potential effectiveness for migraine relief.

Dangers and Drawbacks

While Wild Lettuce offers potential health benefits, it is essential to be aware of the potential dangers and drawbacks associated with its use. Some considerations include:

Allergic Reactions

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Individuals allergic to certain plants like ragweed, daisies, and marigolds may also experience allergic reactions to Wild Lettuce. If you have known allergies, exercise caution and consult with a healthcare professional.

Interaction with Medications

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Wild Lettuce may interact with certain medications, particularly sedatives, anti-anxiety drugs, and pain medications. It is important to consult with a healthcare professional before using Wild Lettuce if you are taking any medications.

Dosage and Preparations

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Wild Lettuce should be used in moderation and according to recommended dosages. Tinctures, extracts, or dried leaves are commonly used preparations. However, it is crucial to follow proper instructions to avoid any potential adverse effects.

Pregnancy and Breastfeeding

pregnancy, rest, people and expectation concept - close up of happy smiling pregnant woman sitting in bed and touching her belly at home
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The safety of Wild Lettuce during pregnancy and breastfeeding is not well-studied. It is advised to avoid using Wild Lettuce during these periods to prevent any potential harm to the fetus or infant.

Sedation and Drowsiness

Sleepy young man rubs his eyes with his right hand. His left hand is on the steering wheel. He is sitting at his car. Road safety concept.
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Due to its sedative properties, Wild Lettuce can cause drowsiness and impair cognitive function. Avoid operating heavy machinery or engaging in activities that require alertness if you have consumed Wild Lettuce.

Lack of Scientific Research

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While Wild Lettuce has a long history of traditional use, scientific research on its effects and safety is limited. As a result, it is essential to approach its use with caution and seek professional advice when necessary.

How Wild Lettuce is Taken

Wild Lettuce is typically taken in a tea form. The leaves are steeped in hot water, which produces a bitter-tasting liquid. It can also be prepared as an infusion (a cold drink made by steeping herbs in water) or tincture (a liquid solution of alcohol and plant-based material). Finally, it is also available in capsule form.

The Bottom Line

Though wild lettuce might have some health benefits, many people are unaware of the adverse side effects that can occur from ingesting this plant. It is crucial to prioritize personal safety and consult with a healthcare professional before incorporating Wild Lettuce into your wellness routine.


  1. Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce-A Comprehensive Review.” Pubmed. Min Shi, et al. June 2022.
  2. Lettuce as an Effective Remedy in Uremic Pruritus: Review of the Literature Supplemented by an In Silico Study.” NCBI. Nazanin Zahra Sepehri, et a. March 29, 2022.
  3. On the Opium of Lettuce.” NCBI. November 1801.