Insights from Fear Suppression Studies

Parallel research at the Sainsbury Wellcome Centre at UCL has revealed how the brain learns to override instinctive fears. By studying mice exposed repeatedly to a harmless visual threat, scientists identified a brain region called the ventrolateral geniculate nucleus (vLGN) that acts as a switch to suppress fear responses over time. This mechanism helps explain how experience can calm anxiety and fear, offering another potential target for therapy.