Chantel Brink

Chantel Brink

June 8, 2025

Researchers Identify Anxiety ‘Off’ Switch That Causes No Side Effects

Insights from Fear Suppression Studies

Grayscale Photography of Woman Touching Her Eyes
Image Credit: Pexels

Parallel research at the Sainsbury Wellcome Centre at UCL has revealed how the brain learns to override instinctive fears. By studying mice exposed repeatedly to a harmless visual threat, scientists identified a brain region called the ventrolateral geniculate nucleus (vLGN) that acts as a switch to suppress fear responses over time. This mechanism helps explain how experience can calm anxiety and fear, offering another potential target for therapy.