In modern society, stress levels have significantly increased, with lifestyle maintenance becoming increasingly demanding. This has almost become the norm, and feeling tired or struggling to sleep is not uncommon. However, if these symptoms are persistent, self-research might lead you to a condition called “adrenal fatigue.”
Adrenal fatigue is a term used to describe persistent tiredness, brain fog, and cravings, which some claim result from the adrenal glands being “overworked” by chronic stress. Its popularity as a diagnosis comes as growing awareness surrounds the impact of stress on mental and physical health. Despite its popularity, adrenal fatigue is not recognized as a legitimate medical diagnosis by mainstream medicine. This is due to there being no scientific evidence to support its existence.
The Role of the Adrenal Glands

The adrenal glands are small, triangular organs located above each kidney. They produce hormones, including cortisol and adrenaline, which help regulate metabolism, blood pressure, and the body’s response to stress. When these glands fail to produce enough hormones, the result is adrenal insufficiency, or Addison’s disease. This is a serious medical condition that requires medical intervention and care.
Origins of the Adrenal Fatigue Theory

The concept of adrenal fatigue was first introduced in 1998 by a chiropractor, not a medical doctor. The theory claims that chronic stress can exhaust the adrenal glands, causing them to underperform and resulting in symptoms like fatigue and low energy. However, there is no scientific evidence that chronic stress alone can cause the adrenal glands to stop functioning properly in this way. “The adrenal glands don’t ‘wear out’ the way this theory suggests, and there is no scientific evidence to back it up.” says Raj Dasgupta, MD, chief medical advisor for Garage Gym Reviews.
Symptoms Attributed to Adrenal Fatigue

People who believe they have adrenal fatigue often report persistent tiredness, difficulty concentrating, and trouble sleeping. They also describe mood swings, cravings for salt and sugar, and a reliance on caffeine. These symptoms are real and can significantly impact daily life, but they are not due to adrenal fatigue.
These symptoms could be caused by many other conditions. Instead of adrenal fatigue, other issues such as thyroid imbalances or iron deficiency could be the underlying cause of these symptoms. Lacking necessary nutrients in your diet may also contribute to persistent tiredness and related health concerns.
Read More: What is Chronic Fatigue Syndrome? (Symptoms, Treatment, Natural Remedies)
The Scientific Perspective

Major medical organizations, including the Endocrine Society, state that there is no scientific proof to support adrenal fatigue as a true medical condition. A systematic review of 58 studies found no evidence that adrenal impairment causes fatigue, and most studies showed no difference in hormone levels between fatigued and healthy individuals. The symptoms people experience are real but not due to adrenal fatigue.
Adrenal Fatigue vs. Adrenal Insufficiency

Most people incorrectly label constant fatigue, stress or burn out as adrenal fatigue. It is also important to distinguish adrenal fatigue and adrenal insufficiency, better known as Addison’s disease. Adrenal insufficiency is a recognized and potentially life-threatening medical condition that can be diagnosed with blood tests and requires hormone replacement therapy.
Read More: 3 Common Signs That Indicate You May Need A Magnesium Supplement
Common Myths About Adrenal Fatigue

A persistent myth is that the adrenal glands can become “exhausted” or “burn out” due to chronic stress. In reality, the adrenal glands do not simply stop working from stress alone. Another myth is that specific supplements can “heal” adrenal fatigue, when in fact, no supplement has been proven to restore adrenal function in this context. However, there are supplements that could help alleviate symptoms such as constant fatigue and stress.
The Impact of Chronic Stress

Chronic stress can impact the body’s hypothalamic-pituitary-adrenal (HPA) axis, which is crucial for regulating cortisol levels. This impact can cause dysregulation and cause symptoms sometimes linked with adrenal fatigue. While stress can cause dysregulation of this system, it does not lead to the adrenal glands “burning out.” Instead, stress-related symptoms are likely due to the body’s overall response to prolonged stress, not adrenal failure.r
Read More: 8 Signs of Potassium Deficiency
Potential Causes of Fatigue

Fatigue can arise from a wide variety of factors. Poor sleep, inadequate nutrition, and a lack of physical activity are frequent contributors to persistent tiredness. This often stems from bad lifestyle habits that can be rectified. Mental health challenges, such as depression, anxiety, or emotional stress, can cause fatigue, sometimes making everyday activities difficult to manage. Additionally, underlying medical conditions like thyroid disorders, anemia, diabetes, or chronic infections may be responsible for ongoing fatigue.
When to Seek Medical Attention

If you experience persistent fatigue, unexplained weight changes, dizziness, or other concerning symptoms, consult your doctor. Early evaluation can help identify treatable conditions such as anemia, thyroid disorders, or adrenal insufficiency. Ensuring you receive appropriate care works best with early intervention, so contact your doctor if you suffer from these symptoms. If fatigue lasts longer than two weeks despite adequate rest, stress management, and proper nutrition, consult a professional immediately.
Read More: How to Spot Chronic Inflammation: 6 Key Symptoms and Solutions
Addressing Symptoms Through Lifestyle Changes

Improving sleep quality, managing stress, eating a balanced diet, and engaging in regular physical activity are effective strategies for addressing symptoms commonly attributed to adrenal fatigue. Mindfulness practices, therapy, and social support can also play important roles in improving overall well-being and reducing stress-related symptoms.
Popular Adaptogens for Adrenal Fatigue

Many people turn to adaptogenic herbs when experiencing symptoms attributed to adrenal fatigue. Ashwagandha, rhodiola, and ginseng are among the most commonly marketed supplements for this condition. These herbs are promoted as natural solutions to combat chronic stress and restore energy levels. Adaptogens work by potentially helping the body manage stress responses more effectively. While adrenal fatigue itself lacks scientific recognition, these supplements attract those seeking alternatives to conventional treatments. Even if its not a recognized condition, these supplements may help with symptoms associated with adrenal fatigue, like stress, engery, and mental focus, but they are not treating any underlying issues that need to be addressed.
Evidence Behind Adaptogenic Benefits

Clinical trials demonstrate that certain adaptogens provide measurable benefits for stress and fatigue symptoms. Rhodiola rosea and Schisandra chinensis show promise in enhancing endurance and cognitive function in people with mild fatigue. Ashwagandha exhibits anti-fatigue effects and may increase mental work capacity against stress. The benefits observed likely relate to general stress management rather than adrenal restoration.
Safety Considerations and FDA Regulation

Supplements marketed for adrenal fatigue are not regulated by the FDA before reaching consumers. Some supplements may interact with medications or cause unwanted side effects in certain individuals. Healthcare providers should always be consulted before starting any new supplement regimen, especially for people with existing health conditions.
Navigating Myths and Realities

Adrenal fatigue is not a recognized medical condition, but the symptoms people experience are real and deserve attention. Addressing chronic stress, improving lifestyle habits, and seeking medical advice when needed are the most effective ways to manage these symptoms. Adaptogens may offer some support for stress, but they do not cure adrenal fatigue. Always consult a healthcare professional before starting any new supplement or treatment.
Disclaimer: This information is not intended to be a substitute for professional medical advice, diagnosis or treatment and is for information only. Always seek the advice of your physician or another qualified health provider with any questions about your medical condition and/or current medication. Do not disregard professional medical advice or delay seeking advice or treatment because of something you have read here.
Read More: Why You’re Always Tired and How Fix Fatigue