Bruce Abrahamse

Bruce Abrahamse

April 17, 2025

Study Reveals Crucial Heart Marker Linked to Ischemic Stroke and Dementia Risk

Researchers at the University of Minnesota Medical School discovered a significant warning sign that may help predict the likelihood of having an ischemic stroke or developing dementia. This research may enable doctors to treat patients earlier and improve their outcomes. The researchers sought to try and identify which sign of left atrial myopathy is the most consistent predictor of dementia and ischemic stroke risk. According to their research, the ability of the left atrium to stretch turned out to be the most effective predictor. 

A Significant Improvement in Dementia and Stroke Risk Prediction

woman with dementia
Credit: PIxabay

According to professor Lin Yee Chen at the U of M Medical School, “Our research offers meaningful improvement in risk prediction beyond traditional clinical factors. Our findings suggest doctors could use this measurement to identify patients who are at higher risk and might need closer monitoring or preventive treatment.” The study involved tracking 4,700 older adults over a period of eight years, observing who developed dementia and strokes. They evaluated multiple measurements of left atrial cardiac function in order to identify which could better anticipate these conditions. 

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Only two of the indicators studied demonstrated a considerable increase in prediction accuracy when added to the conventional risk assessment tool used by doctors. These were the left atrium’s ability to stretch and a specific blood protein marker (NT-proBNP). The left atrium’s ability to distend was the strongest predictor of stroke and dementia. Dr. Chen and his team are planning a large study at several hospitals to see if taking blood thinners can help lower dementia and stroke risk in people with left atrial myopathy. They plan to use a special heart test called left atrial reservoir strain to identify which people with this condition.

What This Means For The Future

man with dementia
Credit: Pixabay

This study could potentially shape how doctors check for stroke and dementia risk in the future. By focusing on the heart’s ability to stretch, healthcare providers might be able to detect abnormalities early and deliver therapies that benefit both heart and brain health. As further research is carried out, this discovery could eventually give rise to new screening tools or routine heart testing for older folks. This could offer them a better chance of staying healthy for longer. 

The University of Minnesota Medical School’s research provides hope for reducing two of the most major health risks to older adults: stroke and dementia. By finding a crucial heart marker associated with these illnesses, clinicians may soon have improved tools for early identification and prevention. Future research will determine whether medicines such as blood thinners can make a difference, but this result is an important step forward in heart and brain health research.

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